Today, we are not looking for tissue compatibility between donor and receiver. The tissue compatibility had relatively more significance 2 decades ago. Since we had only three types of medications available at that time. However, since early 2000’s and especially in last decade, a variety of alternative medications are introduced and thus, we can eliminate problems resulting from tissue incompatibility.
When our patients refer for kidney transplantation, they ask “how much percent tissue compatibility is there between me and my donor?” We do not care about the tissue compatibility our patients ask about. We have some very special tissue tests. We analyze whether there are cells in receiver’s body to overreact against donor tissue. If we do not find those cells, then tissue compatibility has no role in success of organ transplantation.
Who can be organ donor?
Of course, human beings are needed as a source of organ. Because we transplant human organs to human beings. It is possible for people to donate organs, if two conditions are met. Both for cadaver and living donors. Organs are transplanted, which are donated by patients, who are diagnosed with brain death. This is our first source. The second source is living donors, who can donate one of their kidneys or a part of their livers to their relatives, while donor is still alive. These are our main sources of organs in organ transplantation. In Turkey, ratio of cadaveric donor transplantations to total organ transplantation surgeries is 25 percent. However, ratio of living donor transplantations to total organ transplantation surgeries is 75 percent. In this context, despite we fall slightly behind the average of the world in cadaveric organ transplantations, Turkey has total number and success rates of transplantations equivalent to European countries.